RPOL for blind or visually impaired members
I don't remember her name, but there was a user here who was blind, not just visually challenged I was co-DM in a game she played in, but I think she also ran games. I had to help her with picking a suitable portrait for her characters, but I think otherwise I never would have known.
I would expect a blind, or even partially blind, user who wanted to run a game would be wise to have a co-DM, if only to ensure no one was using visuals that were against the rules.
Perhaps you should post a bit about the problems you've had. Someone may be able to suggest work arounds, and jase might even take those into consideration as he updates, especially if they make something easier for everyone.