[IC] Liminal Horror - Beyond Loss
All very good questions!
I actually had something closer to Unknown Armies than World of Darkness in mind, but at a smaller and less comprehensible scale.
I'm currently having thoughts inspired by Junji Itoh comics, some of the smaller scale Cthulhu Mythos stuff, The Ring, Suicide Club, Twin Peaks, Se7en...
The supernatural is real, but it's fairly localised, and very personal. The world's problems can't be blamed on Nyarlathotep or vampires, but on people with ambitions that outweigh their empathy.
Part of why I want the plot to focus on the lost loved ones of each of the characters is to use plot to explore character. Lots of stuff to explore about loss of trust, loss of optimism, and loss of community, while still being driven to solve a deeply personal mystery.
I suspect I'd go with a Mature game, due to horrific subject matter rather than sex.