Depends... do you mean:
Niv-Mizzet, Dracogenius - (Legendary Dragon Wizard, 5/5, 2UURR (6)
Flying
Whenever Niv-Mizzet, Dracogenius deals damage to a player, you may draw a card.
{U}{R}: Niv-Mizzet, Dracogenius deals 1 damage to target creature or player.)
[
http://magiccards.info/rtr/en/183.html]
He has no patience for minds that do not inspire him or explode by trying.
or
Niv-Mizzet, the Firemind - (Legendary Dragon Wizard, 4/4, 2UURR (6)
Flying
Whenever you draw a card, Niv-Mizzet, the Firemind deals 1 damage to target creature or player.
{T}: Draw a card.)
[
http://magiccards.info/mm2/en/182.html]
Either way, it would tempt me to build a dragon or wizard related themed deck. There are plenty of cards that go well together for dragons, and certainly plenty of wizard related cards that go well together. Dual Red/Blue lands are a must of course.
Do a search on the database for cards that are either just blue, just red or multicoloured and are also wizards and then pick out ones that work well together... do the same for dragons and see if there is enough to build on one or the other...