Basilisa:
In Dungeons & Dragons, “act appropriately” might include an option for “Kill the unsolicited giant spider.”
Um, yes? I'm not sure what you think it has to do with Marvel, but Lathalan has the right of it; unless anyone can deal 50-odd damage in one hit, worst case scenario for me is that I start taking death saves (and even then you'd have to be dealing 30-something damage). More likely is that I drop out of Wild Shape and revert to a spluttering, indignant Gnome if I take enough damage, or I run away and introduce myself later.
Either way, this is not a particularly risky play for my character and having a poisoned, unconscious prisoner to interrogate is worth the small risk to himself. Compare this to riskier attempts to subdue the thugs like hitting them with a big hammer or a pointy thing or some kind of mind-bending or flamey death spell, which could easily kill them "by accident".
It's worth bearing in mind that as much as we're all playing characters, we're all Players here too. "It's what my character would do" is a defence that usually only goes so far. To clarify;
I'm giving explicit permission to anyone that wants to attack me in this scene to do so as a "it's what my character would do"; I've presented a scenario where I think it might be appropriate. All I ask is that you don't abuse that permission and act appropriately as both a character and a fellow player.
I do have a question for GM; are we playing this as a "strict initiative order" style game, where we wait for whoever's next in line to post and for you as GM to post results to each character turn, or would you prefer us all to post our actions for the round in whatever order and you post all the results after, or some other method? We seem to have stalled a little waiting on Reth, who might in turn be waiting to see what happened to the thug I attacked. Just looking for some clarity on what's expected. Cheers.